Moral equivalence and the grounds of moral status in stem cell-derived embryo models: a response to de Graeff and De Proost

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Authors: Johnny M Sakr
Cited by: 1
References: 4

Abstract

argue that no intrinsic differences exist between embryos derived from fertilisation and stem cell-derived embryo models (SCEMs) that would justify attributing a higher moral status to the former. Nienke de Graeff and Lien De Proost challenge this claim by emphasising the diversity of SCEMs and by broadening moral evaluation beyond direct moral status to include relational, symbolic and instrumental value. This response argues that their pluralistic framework does not, in fact, undermine moral equivalence in cases where SCEMs successfully instantiate embryo-like human developmental organisation. Once the distinction between properties that ground moral status and considerations that merely shape social or regulatory responses is made explicit, no principled basis remains for differential moral standing. Variation among SCEMs defeats equivalence only where embryo-like organisation is absent; where it is present, moral parity follows. Likewise, relational and instrumental values may justify different governance strategies, but they cannot ground differences in moral worth without collapsing into policy convenience. Rejecting binary thinking does not require denying equivalence where morally relevant features coincide. Either SCEMs fail to model embryos, in which case equivalence never arises, or they succeed and must be treated as morally equivalent in respect of status. What cannot be coherently sustained is embryo-likeness without moral parity.

Fields of Study & Subjects

Pluripotent Stem Cells Research Reproductive Health and Technologies Neuroethics Human Enhancement Biomedical Innovations

Publication details

Journal / source
Journal of Medical Ethics
Publisher
BMJ
Volume
52
Issue
10
Pages
jme–2026
Publication date
8 January 2026
Language
EN