Endovascular treatment and outcome in patients with CTP-defined extra-large infarct core stroke

Journal of NeuroInterventional Surgery 2026 Open access

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Authors: Jinhua Ye, Tingyu Yi, Lan Hong, Ruihan Zhu, Jinfeng Miao, Ding-Lai Lin, Zhengzhou Yuan, Xiao-Hui Lin, Yan-Min Wu, Zhijiao He, Weifeng Huang, Zhi-Nan Pan
+14 more Lisan Zeng, Mei-Hua Wu, Yi-Ning Yang, Cai-Xia Li, Shuyi Liu, Huanghuang Chen, Derong Wu, Qian Sun, Xinguang Yang, Yamei Tang, Meng Zhang, Na Xu, Xin Cheng, Wenhuo Chen
DOI: 10.1136/jnis-2026-025528
Cited by: 0
References: 28

Abstract

BACKGROUND AND PURPOSE: Evidence for endovascular thrombectomy (EVT) in patients with very large perfusion-defined infarct core stroke remains limited. METHODS: We performed a retrospective multicenter cohort study using prospectively maintained stroke registries from nine comprehensive stroke centers in China between 1 June, 2019 and 1 June, 2025. Adults with anterior circulation large-vessel occlusion involving the internal carotid artery or middle cerebral artery M1/M2 segment, presentation within 24 hours, and baseline CT perfusion (CTP)-defined ischemic core volume ≥100 mL were included. Ischemic core was defined as relative cerebral blood flow of

Fields of Study & Subjects

Acute Ischemic Stroke Management Stroke Rehabilitation and Recovery Intracerebral and Subarachnoid Hemorrhage Research

Publication details

Journal / source
Journal of NeuroInterventional Surgery
Publisher
BMJ
Pages
jnis–2026
Publication date
25 June 2026
Language
EN