LBA:01:04 Original research – antiphospholipid syndrome in the pediatric population: performance of ACR-EULAR classification criteria in a controlled cohort

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Authors: Stanley Niznik, Daniel Bar Bar, Shiri Spielman, Rotem Semo-Oz, Assaf Arie Barg, Sarina Levy‐Mendelovich, Gili Kenet, Nancy Agmon-Levin, Irit Tirosh
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Abstract

Objectives APS is a systemic autoimmune disorder marked by thrombotic and non-thrombotic manifestations. In children, diagnosis remains challenging due to lack of validated pediatric criteria. As the 2006 revised Sapporo has been used without validation, and the 2023 ACR-EULAR criteria aim to improve sensitivity by including non-thrombotic features are yet to be validated in this populationThis study evaluates the performance of the ACR-EULAR APS criteria in a pediatric cohort of APS and aPL patients, focusing on key diagnostic parameters and comparison with traditional criteria.Methods A retrospective review of 69 patients‘

Fields of Study & Subjects

Systemic Lupus Erythematosus Research Vasculitis and related conditions Blood Coagulation and Thrombosis Mechanisms

Publication details

Journal / source
Lupus Science & Medicine
Pages
A343.1–A343
Publication date
1 March 2026
Language
EN