PT7:05 Defining the lupus low disease activity state(LLDAS) using the British Isles lupus assessment group index (BILAG-2004): a prospective cohort study

Objectives The Lupus Low Disease Activity State (LLDAS) has been defined as requiring low values of SLE Disease Activity Index (SLEDAI-2K) and Physician Global Assessment (PGA) and predicts lower mortality and damage. The British Isles Lupus Assessment Group Index (BILAG-2004) is an alternative to SLEDAI-2K, incorporating more data. We developed and tested a modified form of LLDAS using BILAG-2004.Methods Demographic, clinical, treatment and laboratory data from 607 individual patients from the University College London Hospital SLE Cohort (2011-2024) were used to determine BILAG-LLDAS and SLEDAI-LLDAS state for each visit. SLEDAI-LLDAS was defined according to the original LLDAS definition, omitting the PGA criterion (