Modeling and Simulation of Open Membranes in Stokes Flow with Mixed-Dimensional Coupling

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Authors: Han Guo Zhou, Yuan‐Nan Young, Yoichiro Mori
Cited by: 1
References: 71

Abstract

Abstract. In this work, we present a mathematical and computational framework to model the dynamics of open lipid bilayer membranes interacting with ambient Stokes flow. The model explicitly couples the three-dimensional viscous fluid, the two-dimensional membrane surface, and its one-dimensional free edge. We develop an axisymmetric hybrid BEM-FEM method that solves the problem with an effective one-dimensional formulation. A key component is a local mesh refinement strategy designed to accurately resolve singularities and boundary layers originating at the membrane edge. Several numerical examples are provided to showcase its ability to capture intricate edge dynamics and multiscale fluid-membrane coupling.

Fields of Study & Subjects

Membrane Separation Technologies

Publication details

Journal / source
Multiscale Modeling and Simulation
Publisher
Society for Industrial & Applied Mathematics (SIAM)
Volume
24
Issue
2
Pages
474–500
Publication date
13 April 2026
Language
EN