Hele–Shaw limit of chemotaxis-Navier–Stokes flows

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Authors: Qingyou He, Ling-Yun Shou, Leyun Wu
Cited by: 0

Abstract

This paper investigates the connection between the chemotaxis-Navier–Stokes system with porous medium-type nonlinear diffusion and the Hele–Shaw problem in [Formula: see text] ([Formula: see text]). First, we prove the global-in-time existence of weak solutions for the Cauchy problem of the chemotaxis-Navier–Stokes system with general initial data, uniformly in the diffusion range [Formula: see text]. In particular, this existence result does not require additional structural assumptions on the chemotactic sensitivity [Formula: see text] and the oxygen consumption rate [Formula: see text], and remains valid in arbitrary dimensions. Then, we rigorously justify the Hele–Shaw limit for this system as [Formula: see text], showing the convergence to a free boundary problem of Hele–Shaw type, where the bacterium (cell) diffusion is governed by the stiff pressure law. Moreover, the complementarity relation characterizing the limiting bacterium (cell) pressure via a degenerate elliptic equation is verified by a novel application of the Hele–Shaw framework.

Fields of Study & Subjects

Mathematical Biology Tumor Growth MRI in cancer diagnosis

Publication details

Journal / source
Mathematical Models and Methods in Applied Sciences
Publisher
World Scientific Pub Co Pte Ltd
Pages
1–40
Publication date
18 July 2026
Language
EN