J-Editing Proton MR Spectroscopy for Brain Signal Separation in Methylmalonic Acidemia: A Pediatric Case-Control Study

Radiology 2026

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Authors: Mengyuan Zhuo, Yan Yun, Jiaxiang Xin, Aocai Yang, Yufan Chen, Y L Zhao, Guangbin Wang
DOI: 10.1148/radiol.251117
Cited by: 1
References: 21

Abstract

J-editing proton MR spectroscopy enabled in vivo separation of cerebral methylmalonic acid (MMA) and lactate signals in methylmalonic acidemia, and the MMA signal intensity correlated with blood propionylcarnitine to acetylcarnitine ratio and urinary MMA levels.

Fields of Study & Subjects

Metabolism and Genetic Disorders Folate and B Vitamins Research Advanced MRI Techniques and Applications

Publication details

Journal / source
Radiology
Publisher
Radiological Society of North America (RSNA)
Volume
318
Issue
3
Pages
e251117–e251117
Publication date
1 March 2026
Language
EN