MRI-guided versus OSEM Amyloid Brain PET Reconstruction for Reader Agreement, Visual Consistency, and Diagnostic Accuracy

Radiology 2026

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Authors: Yu Cai, Chen Lin, Manoj Kumar Jain, Robert A. Pooley, Brittany L. Benson, Jun Zhang, Matthew G. Spangler‐Bickell, Alex K. Smith, Vivek Gupta, Catherine Bullock, Erik H. Middlebrooks, Neetu Soni
DOI: 10.1148/radiol.260692
Cited by: 1
References: 39

Abstract

MRI-guided amyloid brain PET reconstruction showed higher interreader agreement and fewer false-positive classifications than ordered-subset expectation-maximization reconstruction and preserved Centiloid-based separation between the β-amyloid negative and positive groups.

Fields of Study & Subjects

Advanced MRI Techniques and Applications Medical Imaging Techniques and Applications Functional Brain Connectivity Studies

Publication details

Journal / source
Radiology
Publisher
Radiological Society of North America (RSNA)
Volume
320
Issue
3
Pages
e260692–e260692
Publication date
1 September 2026
Language
EN