Pediatric Rheumatic Disorders Revisited: Integrating Imaging and Pathophysiologic Insights across the Autoinflammatory-Autoimmune Continuum

Radiographics 2026

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Authors: Yuko Tsujioka, Atsuhiko Handa, Gen Nishimura, Masaru Takeshita, Yoshitake Yamada, Eugene Nishi, Tatsuo Kono, Masahiro Jinzaki
DOI: 10.1148/rg.250120
Cited by: 1
References: 57

Abstract

Pediatric rheumatic diseases are a diverse group of immune-mediated disorders classically divided into (a) autoimmune diseases as a result of dysregulated adaptive immunity and (b) autoinflammatory diseases of aberrantly activated innate immunity, but their clinical, immunologic, and genetic overlap has led to a new perspective on the autoinflammatory-autoimmune continuum, impacting imaging practice and decision making in medical intervention.

Fields of Study & Subjects

Inflammasome and immune disorders Systemic Lupus Erythematosus Research Autoimmune and Inflammatory Disorders Research

Publication details

Journal / source
Radiographics
Publisher
Radiological Society of North America (RSNA)
Volume
46
Issue
6
Pages
e250120–e250120
Publication date
28 May 2026
Language
EN