Cardiac Radiation Dose and Subclinical Coronary Artery Disease Progression after Breast Cancer Radiotherapy: 2-year Cardiac CT Results from the EARLY-HEART Study

Radiology Cardiothoracic Imaging 2026

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Authors: Elie Mousseaux, Damian Craiem, Rozemarijn Vliegenthart, Sophie Jacob, Arantxa Eraso, Susana Constantino Rosa Santos, Kai Borm, Johannes Albertus Langendijk, Médéa Locquet, Montse Ventura, Manuela Fiuza, Stephanie E. Combs
+4 more Daan S. Spoor, Anne P.G. Crijns, for the MEDIRAD EARLY-HEART investigators, Susana Constantino
DOI: 10.1148/ryct.250342
Cited by: 1
References: 28

Abstract

Two years after breast cancer radiotherapy, cardiac CT demonstrated dose-associated progression of coronary artery calcification, particularly in the presence of preexisting calcification, while coronary stenosis progression was unrelated to radiation dose.

Fields of Study & Subjects

Cardiac Imaging and Diagnostics Chemotherapy-induced cardiotoxicity and mitigation Breast Cancer Treatment Studies

Publication details

Journal / source
Radiology Cardiothoracic Imaging
Publisher
Radiological Society of North America (RSNA)
Volume
8
Issue
3
Pages
e250342–e250342
Publication date
21 May 2026
Language
EN