Impact of nesting materials on energy balance in male C57BL/6J mice exposed to different ambient temperatures
Abstract
Nesting availability, but not nesting material type, modulates energy metabolism in individually housed male mice in a temperature-dependent manner. Nesting reduces metabolic demand at standard housing temperature, with minimal impact at thermoneutrality. These findings support the use of common nesting materials and highlight the importance of reporting environmental enrichment to improve rigor and reproducibility in metabolic studies.
Fields of Study & Subjects
Animal Behavior and Welfare Studies
Physiological and biochemical adaptations
Adipose Tissue and Metabolism
Publication details
- Journal / source
- American Journal of Physiology-Endocrinology and Metabolism
- Volume
- 330
- Issue
- 4
- Pages
- E479–E487
- Publication date
- 24 February 2026
- Language
- EN