3D echo derived right ventricular principal surface strain in pulmonary arterial hypertension

American Journal of Physiology-Heart and Circulatory Physiology 2026 Open access

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Authors: Hannah Takahashi Oakland, Lavanya Bellumkonda, Lissa Sugeng, Phillip Joseph, Priyamvada Kundu, Daniel Izzi, Felica Zalik, Shannon Mccabe, Amjad Ali Raza, Ray Amendola, Paul M. Heerdt, Kendall Hunter
+1 more Inderjit Singh
DOI: 10.1152/ajpheart.00923.2025
Cited by: 1
References: 40

Abstract

Impaired PS Max is associated with worse RV systolic function and outcomes in PAH when compared with conventional 2-D metrics of RV systolic function, while ϴ Max is progressively oriented longitudinally in PAH patients with RH failure compared to those without RH failure, potentially reflecting an echocardiographic representation of maladaptive RV myofiber reorientation. PS Max and ϴ Max represent a powerful and concise way to describe RV systolic function that may prove useful in the care of PAH patients.

Fields of Study & Subjects

Pulmonary Hypertension Research and Treatments Cardiovascular Function and Risk Factors Cardiac Valve Diseases and Treatments

Publication details

Journal / source
American Journal of Physiology-Heart and Circulatory Physiology
Publisher
American Physiological Society
Volume
330
Issue
3
Pages
H729–H736
Publication date
30 January 2026
Language
EN