Completion of Fontan circulation does not affect the low longitudinal contribution to stroke volume in patients with single ventricles

American Journal of Physiology-Heart and Circulatory Physiology 2026 Open access

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Authors: Pia Sjöberg, Petter Frieberg, Zahraa Alsafi, Petru Liuba, Håkan Arheden
DOI: 10.1152/ajpheart.00959.2025
Cited by: 0
References: 17

Abstract

This study shows that patients with single ventricles exhibit lower longitudinal systolic function than healthy subjects. The longitudinal contribution to stroke volume was about 40% compared with ∼80% in a normal right ventricle and 60% in a normal left ventricle. This difference is likely related to the passive blood flow through the lungs and did not change after Fontan completion. Furthermore, atrioventricular coupling seems to be preserved despite previous pericardiotomies.

Fields of Study & Subjects

Congenital Heart Disease Studies Cardiovascular Function and Risk Factors Cardiomyopathy and Myosin Studies

Publication details

Journal / source
American Journal of Physiology-Heart and Circulatory Physiology
Volume
330
Issue
3
Pages
H722–H728
Publication date
31 January 2026
Language
EN