Rapid podocyte loss in murine models triggers the formation of podocyte-parietal epithelial cell intercellular bridges

American Journal of Physiology-Renal Physiology 2026 Open access

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Authors: Nina Cintron Pregosin, Yiqing Guo, Emily T. Dang, Nehaben A. Gujarati, Monica Patricia Revelo, Fatima Danish Sheikh, Randolph Alexander Hennigar, David J. Salant, Vivette D. D’Agati, Sandeep K. Mallipattu
DOI: 10.1152/ajprenal.00292.2025
Cited by: 1
References: 64

Abstract

To date, this is the first study to demonstrate that intercellular bridges form between podocytes and parietal epithelial cells in the setting of rapid podocyte loss in subtypes of glomerulonephritis and FSGS.

Fields of Study & Subjects

Renal Diseases and Glomerulopathies Genetic and Kidney Cyst Diseases Extracellular vesicles in disease

Publication details

Journal / source
American Journal of Physiology-Renal Physiology
Publisher
American Physiological Society
Volume
330
Issue
2
Pages
F223–F237
Publication date
2 January 2026
Language
EN