Jugular venous flow dynamics during acute weightlessness and partial gravity in parabolic flight

Journal of Applied Physiology 2026

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Authors: Jason R. Lytle, Annelise E. Miller, David S. Martin, Christopher A. Miller, Millennia Young, Steven S. Laurie, Brandon Richard Macias, Stuart M. C. Lee
DOI: 10.1152/japplphysiol.00032.2025
Cited by: 1
References: 65

Abstract

Weightlessness-induced blood flow stasis in internal jugular veins (IJV) may contribute to an increased risk of thrombosis during spaceflight. Here we report that reduced gravity leads to IJV distension in healthy participants and that 0.00-G, 0.25-G, and 0.50-G exposures resulted in stagnant blood flow in the left IJV in one participant. Reduced gravity on the Moon and Mars may be insufficient to protect against venous flow abnormalities.

Fields of Study & Subjects

Spaceflight effects on biology Cardiovascular and Diving-Related Complications High Altitude and Hypoxia

Publication details

Journal / source
Journal of Applied Physiology
Publisher
American Physiological Society
Volume
140
Issue
4
Pages
946–957
Publication date
2 March 2026
Language
EN