The effect of nasal patency and anatomy during asymmetrical nasal high flow

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Authors: Monique Rees, Fernando Vieira, Sasi Bhushan Yarragudi, Matthew J. Barnes, Stanislav Tatkov
Cited by: 1
References: 25

Abstract

The asymmetrical cannula interface used during nasal high flow (NHF) causes unequal occlusion of the nares. This study demonstrates that physiological changes of nasal patency at the internal nasal valve, known as the nasal cycle, do not affect ventilation during NHF. In contrast, anatomical variability, such as differences in the cross-sectional area of the nares or severe nasal septum deviation, may substantially influence the generated pressure and could produce physiologically relevant effects during therapy.

Fields of Study & Subjects

Nasal Surgery and Airway Studies Sinusitis and nasal conditions Airway Management and Intubation Techniques

Publication details

Journal / source
Journal of Applied Physiology
Publisher
American Physiological Society
Volume
140
Issue
5
Pages
1159–1168
Publication date
28 March 2026
Language
EN