Aging slows maximum shortening velocity and reduces peak power output of rat diaphragm muscle

Journal of Applied Physiology 2026 Open access

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Authors: Genesis Hernandez-Vizcarrondo, Matthew Joseph Fogarty, Humzah S. Abdulkader, Lucy Sieck, Carlos Bernardo Mantilla, Gary Charles Sieck
DOI: 10.1152/japplphysiol.00148.2026
Cited by: 1
References: 65

Abstract

Aging selectively impacts the function of type IIx/IIb fibers in the diaphragm muscle. We show that sarcopenia reduces maximum specific force, maximum shortening velocity, and peak power output, whereas endurance during repetitive contractions is preserved. These findings explain why higher force airway clearance behaviors decline with age, whereas fatigue-resistant breathing behavior remains resilient.

Fields of Study & Subjects

Muscle Physiology and Disorders Nutrition and Health in Aging Cardiovascular and exercise physiology

Publication details

Journal / source
Journal of Applied Physiology
Publisher
American Physiological Society
Volume
141
Issue
1
Pages
194–204
Publication date
12 June 2026
Language
EN