Misconceptions about variance comparisons for exploring the presence of treatment response heterogeneity in randomized controlled trials
Abstract
Letter to the Editor. To the editor: Regarding treatment response heterogeneity (TRH), we contest claims in Ref. 1 about variance difference statistics, especially the standard deviation of individual responses (SDIR).
Fields of Study & Subjects
Advanced Causal Inference Techniques
Statistical Methods in Clinical Trials
Statistical Methods and Bayesian Inference
Publication details
- Journal / source
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Volume
- 140
- Issue
- 1
- Pages
- 206–207
- Publication date
- 1 January 2026
- Language
- EN