Intensity-dependent corticospinal facilitation by repetitive peripheral magnetic stimulation: evidence for a major contribution of group I afferents

Journal of Neurophysiology 2026

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Authors: Kaito Yoshida, Mitsuhiro Nito, Dai Miyazaki, Ayu Omiya, Kanau Shitara, Tadaki Koseki, Daisuke Kudo, Nariyuki Mura, Hiromi Fujii, Tomofumi Yamaguchi
DOI: 10.1152/jn.00633.2025
Cited by: 1
References: 41

Abstract

Repetitive peripheral magnetic stimulation (PMS) facilitates corticospinal excitability in an intensity-dependent manner and requires suprathreshold intensities. High-intensity PMS acts faster than lower-intensity suprathreshold stimulation, whereas subthreshold stimulation does not significantly modulate corticospinal excitability. This facilitation is abolished by ischemia and linked to short-latency motor unit responses, supporting a major contribution of large-diameter group I afferent input with a substantial Ia component. These findings inform optimization of PMS protocols for neurorehabilitation.

Fields of Study & Subjects

Transcranial Magnetic Stimulation Studies Spatial Neglect and Hemispheric Dysfunction Sport Psychology and Performance

Publication details

Journal / source
Journal of Neurophysiology
Publisher
American Physiological Society
Volume
135
Issue
6
Pages
1455–1466
Publication date
1 May 2026
Language
EN