Mapping the Scientific Landscape of Neuropathic Pain in Sickle Cell Disease: A Two‐Decade Bibliometric Perspective on an Underexplored Challenge

Background Neuropathic pain is often underdiagnosed and undertreated in individuals with sickle cell disease (SCD), particularly in regions where the disease is prevalent. Despite its significant impact on quality of life and the healthcare system, the extent to which this issue has been explored in the scientific literature remains unclear. This study aimed to conduct the first bibliometric analysis focused on neuropathic pain in SCD, identifying global research trends, key contributors, and critical knowledge gaps. Methods We searched the Web of Science, Scopus, PubMed, SciELO, and LILACS for publications from the past 20 years. Article selection followed PRISMA guidelines. Bibliometric analysis was performed using Bibliometrix and VOSviewer software. Results Thirty‐seven studies met the inclusion criteria, revealing a limited body of research on this topic. Publications originated from seven countries, with the United States being the most productive. Research output showed a modest increase from 2019 to 2021. The most common keywords included “children,” “management,” and “questionnaire,” highlighting a clinical and pediatric‐oriented trend. Notably, “children” was not a search descriptor but an emerging keyword from the bibliometric analysis. Institutional and geographic concentration was evident, with the University of Illinois Chicago leading in productivity. Conclusions This study highlights a significant gap between the clinical importance of neuropathic pain in SCD and the limited scientific interest it has received worldwide. The few publications emphasize the urgent need for coordinated, multicenter efforts—especially in high‐prevalence areas—to advance research, enhance clinical outcomes, and address disparities in care.