Topical Chlorhexidine‐Induced Oral Allergic Reaction: A Case Report

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Authors: Matteo Zotti, Katia Rupel, Marina Diolosà, Giulia Ottaviani
Cited by: 1
References: 8

Abstract

This case report describes a rare episode of allergic reaction to the topical application of chlorhexidine gel. The patient, following the prescription from her private dentist, presented to the dental emergency unit, referring to the onset of an increasing swelling of the upper lip a few hours after the application of chlorhexidine gel. After the exclusion of a possible infective process starting from the maxillary incisors, the patient was prescribed prednisone and exhibited a quick remission of the swelling. This report aims to emphasize the importance of a correct differential diagnosis to warrant an optimal therapeutic approach to the patient, since swellings of the upper lip could be related to different conditions.

Fields of Study & Subjects

Contact Dermatitis and Allergies Drug-Induced Adverse Reactions Skin Protection and Aging

Publication details

Journal / source
Case Reports in Medicine
Publisher
Wiley
Volume
2026
Issue
1
Pages
2841092–2841092
Publication date
1 January 2026
Language
EN