Dysrhythmia due to Verapamil Overdose in a Young Woman
Abstract
Verapamil (VER) is characterized as a calcium channel blocker (CCB) that can be intentionally or unintentionally overdosed. This drug, like other CCBs, inhibits the entry of calcium into vascular and myocardial tissues through L-type channels. VER exerts negative inotropic and chronotropic effects on the myocardium through antagonistic L-type calcium channels, and an overdose of this drug can result in a decrease in cardiac output, hypotension, and shock. In this report, we describe a unique case of VER toxicity in a 30-year-old woman who experienced a dysrhythmia and heart block after intentionally ingesting 800 mg of sustained-release VER tablets.
Fields of Study & Subjects
Poisoning and overdose treatments
Cardiac electrophysiology and arrhythmias
Ion channel regulation and function
Publication details
- Journal / source
- Case Reports in Cardiology
- Publisher
- Wiley
- Volume
- 2026
- Issue
- 1
- Pages
- 8747772–8747772
- Publication date
- 1 January 2026
- Language
- EN