Metastatic Melanoma Mimicking Primary Breast Cancer—A Diagnostic Challenge: A Case Report

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Authors: Angela de Salles Rezende, Teresa Cristina Ferreira Gutman, MARCUS VINICIUS TEIXEIRA CALEJON STUMPF, Karin Soares Cunha, Fabiana Resende Rodrigues, Vânia Glória Silami Lopes
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Abstract

Introduction: Metastatic melanoma to the breast is rare and may be misdiagnosed as primary breast carcinoma. Histological, immunohistochemical, and clinical correlations, such as a history of previous melanoma, are essential for diagnosis. Patient Presentation: A female patient presented with melanoma in the left gluteal region. Five years later, a palpable nodule was detected in the right breast on routine mammography. Microscopic and immunohistochemical examination confirmed the diagnosis of metastatic melanoma. The patient passed away 3 years later. Conclusion: The findings in this case indicate that metastatic melanoma can present in atypical ways and that specialists should pay attention to metastases in unusual locations in cases of melanoma.

Fields of Study & Subjects

Cutaneous Melanoma Detection and Management Metastasis and carcinoma case studies Breast Lesions and Carcinomas

Publication details

Journal / source
Case Reports in Pathology
Volume
2026
Issue
1
Pages
8820195–8820195
Publication date
1 January 2026
Language
EN