Pathological Study of Rare Malignant Cardiac Tumors: A Case Series of Five Patients

Malignant cardiac tumors are uncommon but highly aggressive growths that may develop within the heart or spread from other primary locations. Considering the significance of pathological studies and the dissemination of findings on malignant cardiac tumors in advancing medical knowledge and informing future research in this complex area, this study is aimed at presenting cases of malignant cardiac tumors identified in patients treated at the Rajaie Hospital, Tehran, Iran. In this study, we focused on five cases of malignant cardiac tumors documented in the hospital's surgical pathology archives spanning from 2020 to 2024. The identified tumors consisted of invasive thymoma, diffuse large B-cell lymphoma, primary cardiac synovial sarcoma, primary undifferentiated pleomorphic sarcoma, and metastatic renal cell carcinoma, all classified as rare cardiac neoplasms.