Unmasking Lupus: Intracranial Hemorrhage as the Primary Clue in an Adolescent With Refractory Thrombocytopenia—A Case Report
Abstract
Systemic lupus erythematosus (SLE) is a rare autoimmune disorder, rarely presenting with central nervous system (CNS) hemorrhage-especially cerebellar involvement. We report a previously healthy 17-year-old female presenting with severe thrombocytopenia and cerebellar hemorrhage, leading to a diagnosis of SLE. Recovery was dramatic and achieved by prompt multidisciplinary management, including neurosurgical intervention, immunosuppressive treatment, and intensive care. The case highlights the importance of considering SLE as a differential diagnosis of unexplained intracranial hemorrhage, particularly in adolescents presenting with cytopenia.
Fields of Study & Subjects
Systemic Lupus Erythematosus Research
Vasculitis and related conditions
Platelet Disorders and Treatments
Publication details
- Journal / source
- Case Reports in Pediatrics
- Volume
- 2026
- Issue
- 1
- Pages
- 7996356–7996356
- Publication date
- 1 January 2026
- Language
- EN