Application of Local Hyperthermia Therapy Based on Immune Cell Function in Cutaneous Infectious Diseases

Hyperthermia represents a physiological state marked by an elevation in body temperature due to the malfunctioning of thermoregulatory mechanisms. It transpires when the body either generates or absorbs a greater amount of heat than it is capable of expelling. In clinical practice, hyperthermia has gained increasing recognition compared with traditional laser, freezing, and other treatment measures. However, the regulatory effects of hyperthermia on immune cells and the underlying mechanisms remain insufficiently investigated. In this review, we summarized the therapeutic methods of hyperthermia including thermal water hyperthermia, infrared radiation (IR) hyperthermia, photodynamic therapy, and targeted radiofrequency hyperthermia in dermatology, the clinical practical applications as well as the treatment mechanism based on immune cells. Further studies should be conducted to clarify the underlying mechanisms and promote the clinical applications of hyperthermia.