Assessment of Nutraceutical Potential of Melastoma malabathricum L. Fruits: DPPH, α ‐Glucosidase Inhibition, and LC‐HRMS Analysis

Melastoma malabathricum L., locally known as Angeri in Nepal, is traditionally valued for its health benefits. This study assessed the methanol extract of its ripe fruit for nutritional and medicinal properties. Key findings include high phenolic (119 mg GAE/g) and flavonoid (27.79 mg QE/g) content, along with 0.745 mg of vitamin C per 500 mg dry fruit. The extract showed strong antioxidant activity (IC 50 = 4.99 ± 0.11 μ g/mL) and potent α ‐glucosidase inhibition (IC 50 = 3.28 ± 0.18 μ g/mL). Micronutrient analysis revealed the presence of potassium (7100 ppm), sodium (466.40 ppm), manganese (128.85 ppm), and iron (153.56 ppm). Total sugar content was found to be relatively low (39.06 ± 1.15 mg/g of dry fruit). LC‐HRMS analysis via GNPS identified 13 bioactive compounds, including cyanidin 3‐glucoside cation and (−)‐catechin gallate. These results highlight the nutraceutical richness of M. malabathricum L. fruits and provide baseline data to support further research on the future commercialization.