Research Review on Inhibitors of Lumpy Skin Disease Virus: From Biological Characteristics, Drug Repurposing, to Computer‐Aided Drug Design
Abstract
This review summarizes the research progress on inhibitors of lumpy skin disease virus (LSDV), focusing on its biological characteristics and key proteins involved in the viral replication cycle. It compiles various inhibitors (direct-acting poxvirus inhibitors and host-directed poxvirus inhibitors) against poxviruses, their mechanisms of action, and potential targets, aiming to provide references for the development of LSDV inhibitors. Additionally, the application of computer-aided drug design methods in anti-LSDV inhibitor research is discussed, offering insights from the perspective of virtual screening to facilitate the discovery of novel antiviral agents.
Fields of Study & Subjects
Poxvirus research and outbreaks
Computational Drug Discovery Methods
vaccines and immunoinformatics approaches
Publication details
- Journal / source
- International Journal of Microbiology
- Volume
- 2026
- Issue
- 1
- Pages
- 2663212–2663212
- Publication date
- 1 January 2026
- Language
- EN