Investigation of the Effectiveness of First Measured Arterial/Cord Blood Gas and Laboratory Results in Predicting the Treatment Model in Newborns Diagnosed With Transient Tachypnea

Objective The aim of this study was to investigate the predictive effect of laboratory results and blood gas values on the selection of respiratory support models in infants diagnosed with transient tachypnea of the newborn (TTN). Method The study was designed as a single‐center, retrospective study. Infants born with gestational age ≥ 35 weeks diagnosed with TTN during a 2‐year period were included. Demographic characteristics, laboratory parameters, respiratory support models, and length of hospital stay were recorded. The relationship between the obtained parameters and the percentage and duration of oxygen requirement, nasal continuous positive airway pressure (nCPAP), nasal synchronized intermittent mandatory ventilation (nSIMV), intubation, and hospitalization duration was evaluated. Results The study was completed with 327 infants. A correlation was found between pH and pCO2 values in the first blood gas analysis and the duration of oxygen administration ( p : 0.019 and p : 0.001), and between serum calcium levels and peak sodium levels and the duration of nSIMV ( p : 0.04 and p : 0.023). Low serum calcium, phosphorus, and initial sodium levels were identified in infants requiring invasive ventilation ( p : 0.001, p : 0.006, and p : 0.012, respectively). In the ROC analysis used to predict intubation, the cutoff value for calcium was determined as < 8.11 mg/dL (AUC 0.771, [95% CI: 0.669–0.872], p :