Supplementary Figure S5 from Stress Promotes Lung Metastasis in Breast Cancer by Altering Neutrophil Differentiation

Impact of chronic stress on 4T1 tumor progression and pulmonary metastasis in BALB/c mice (orthotopic mammary fat pad model). A. Images of tumors from mice in both CS and NC groups. B. Quantitative analysis of the tumor weights in A. Data are presented as the mean ± SEM (n = 20). C. Hematoxylin and eosin (HE) staining of paraffin-embedded lung tissue sections from each mouse in the NC or CS group. D. Representative images of primary single-cell lung cultures from NC and CS mice showing the formation of cell clones in vitro. CS, chronic stress; NC, negative control.