Supplementary Figure S13 from Stress Promotes Lung Metastasis in Breast Cancer by Altering Neutrophil Differentiation

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Authors: Pengfei Liu, Jie Zheng, Wenjing Ma, Jinhui Lü, Qian Zhao, Danni Li, Xiaoyan Jiang, Haikun Wang, Haiyun Wang, Zuoren Yu
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Abstract

DEGs in HoxB8 neutrophils with or without knockout of C/EBPβ. A. Differentially expressed genes (DEGs) in zymosan-induced HoxB8 neutrophils between wild type (WT) and knockout (KO) of Cebpb. DEGs with p < 0.005, fold change >2 were highlighted in red. B. Expression level of Ccl3 and Ccl4 in WT and Cebpb-KO HoxB8 neutrophils. C. Gene set enrichment analysis (GSEA) analysis of cell chemotaxis in WT and Cebpb-KO HoxB8 neutrophils. D. Bubble plot displaying the top 10 activated and top 10 suppressed pathways in GSEA-GO analysis of DEGs between WT and Cebpb-KO HoxB8 neutrophils.

Fields of Study & Subjects

Cancer Research and Treatments S100 Proteins and Annexins Immune cells in cancer

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Publication date
2 January 2026