Supplementary Figure 5 from Targeting Interactions Between Siglec-10 and α3β1 Integrin Enhances Macrophage-Mediated Phagocytosis of Pancreatic Cancer

Pratima Saini; Gauri Mirji; S.M. Shamsul Islam; Lacy M. Simons; Smita Bhat; Amanda Pires Bonfanti; Kar Muthumani; Priyesh Agrawal; Joel A. Cassel; Hsin‐Yao Tang; Hiroaki Tateno; Rugang Zhang; Judd F. Hultquist; Rahul Suresh Shinde; Mohamed Ahmed Abdel-Mohsen

doi:10.1158/0008-5472.30985907

Supplementary Figure 5 from Targeting Interactions Between Siglec-10 and α3β1 Integrin Enhances Macrophage-Mediated Phagocytosis of Pancreatic Cancer

2026 Open access

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Authors: Pratima Saini, Gauri Mirji, S.M. Shamsul Islam, Lacy M. Simons, Smita Bhat, Amanda Pires Bonfanti, Kar Muthumani, Priyesh Agrawal, Joel A. Cassel, Hsin‐Yao Tang, Hiroaki Tateno, Rugang Zhang

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Judd F. Hultquist, Rahul Suresh Shinde, Mohamed Ahmed Abdel-Mohsen

DOI: 10.1158/0008-5472.30985907

Cited by: 0

Abstract

Flow cytometry and functional assays showing that ITGA3 knockout reduces Siglec-10 binding and that ITGB1 expression enables PDAC cells to evade macrophage-mediated phagocytosis

Fields of Study & Subjects

Cell Adhesion Molecules Research Immune cells in cancer Phagocytosis and Immune Regulation

Publication details

Publication date: 2 January 2026