Supplementary Figure S4 from Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer

2026 Open access

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Authors: Fatima Alhourani, Marine Tauziet, Margaux Ayeul, Pierre Dambrun, Hiba Daher, Julie Patouillard, Benoît Miotto, Aurélie Gennetier, Simon George, Xavier Mialhe, Mona Dergham, Florence M. Cammas
+8 more Adeline Torro, Diego Tosi, Céline Gongora, Philippe Pourquier, Cyril Ribeyre, Véronique Baldin, Raghida Abou Merhi, Eric Julien
DOI: 10.1158/0008-5472.30986361
Cited by: 0

Abstract

Figure S4 shows the lethal synergy profiles of various prostate cancer cell lines for the combination of etoposide with A-196, and of PC3 cells with EZH2 inhibitor.

Fields of Study & Subjects

Cancer therapeutics and mechanisms Histone Deacetylase Inhibitors Research Chemical Reactions and Isotopes

Publication details

Publisher
American Association for Cancer Research (AACR)
Publication date
2 January 2026