Supplementary Figure S12 from Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer

2026 Open access

Read full text
Authors: Fatima Alhourani, Marine Tauziet, Margaux Ayeul, Pierre Dambrun, Hiba Daher, Julie Patouillard, Benoît Miotto, Aurélie Gennetier, Simon George, Xavier Mialhe, Mona Dergham, Florence M. Cammas
+8 more Adeline Torro, Diego Tosi, Céline Gongora, Philippe Pourquier, Cyril Ribeyre, Véronique Baldin, Raghida Abou Merhi, Eric Julien
DOI: 10.1158/0008-5472.30986376
Cited by: 0

Abstract

Figure S12 shows the levels of H4K20 methylation and of I-SceI in U2OS-derived GCS5 (NHEJ) and RG37 (HR) cell lines treated with A-196 during four days prior to I-SceI expression.

Fields of Study & Subjects

Cancer therapeutics and mechanisms Histone Deacetylase Inhibitors Research Chemical Reactions and Isotopes

Publication details

Publisher
American Association for Cancer Research (AACR)
Publication date
2 January 2026