Figure S2 from PAK5-Mediated Suppression of β-Hydroxybutyrate Production Promotes Breast Cancer Metastasis and Can Be Overcome with Ketogenic Diet

2026 Open access

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Authors: Yao Xing, Yuen Tan, Bingtao Hu, Hongyan Zhang, Yanshu Li, Jinyu Zuo, Yidu Liu, Fuyi Han, Shulan Sun, Xu Wang, Yang Li, Feng Sheng Li
DOI: 10.1158/0008-5472.31744869
Cited by: 0

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Abstract

Supplementary Figure 2. HMGCS2 is identified as a candidate protein regulated by PAK5 in a quantitative proteomic analysis (a) Purification of mitochondria in MDA-MB-231 cells stably expressing Flag vector, Flag-PAK5 and IB analysis of the PAK5 level in MDA-MB-231 cells. (b) HMGCS2 was identified by mass spectrometry (MS) as a protein associated with mitochondrial metabolism and specifically regulated by PAK5.

Fields of Study & Subjects

Cancer Lipids and Metabolism Hypoxia Diet and metabolism studies

Publication details

Publication date
16 March 2026
Language
EN