Figure S1 from PAK5-Mediated Suppression of β-Hydroxybutyrate Production Promotes Breast Cancer Metastasis and Can Be Overcome with Ketogenic Diet

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Authors: Yao Xing, Yuen Tan, Bingtao Hu, Hongyan Zhang, Yanshu Li, Jinyu Zuo, Yidu Liu, Fuyi Han, Shulan Sun, Xu Wang, Yang Li, Feng Sheng Li
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Abstract

Supplementary Figure 1. β-HB is ubiquitous across breast cancer subtypes and non-toxic to normal breast epithelial cells (a) The β-HB levels of serum from breast cancer patients with Luminal A (n = 19), Luminal B (n = 23), Her2+ (n = 8) and TNBC (n = 2). (b) CCK8 proliferation analysis of HBL100 cells, the data were presented as a histogram of the mean and SEM of three independent experiments, n.s. stands for not significant.

Fields of Study & Subjects

Cancer Lipids and Metabolism Hypoxia Diet and metabolism studies

Publication details

Publication date
16 March 2026
Language
EN