Supplementary Table S5 from PI3Kα Inhibitor and Degrader Inavolisib Can Co-opt FGFR2 to Enhance Responses in Patients with PIK3CA-Mutated Solid Tumors and in Preclinical Models

2026 Open access

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Authors: Dejan Juric, Kyung Song, Radia Marie Johnson, Melissa Kate Accordino, Philippe Lucien Bedard, Andrés Cervantes, Valentina Gambardella, Erika Paige Hamilton, Antoîne Italiano, Kevin M. Kalinsky, Ian E. Krop, Mafalda Oliveira
+34 more Cristina Saura, Peter Schmid, Nicholas C. Turner, Andreea Varga, Steven B. Gendreau, Michael S.H. Hwang, Zheng Kuang, Jeffrey Lau, Eva Lin, Trang Pham, Danilo Maddalo, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Scott E. Martin, Nicole M. Sodir, Ethan S. Sokol, Zachary J. Whitfield, Alice Wong, Robert L. Yauch, Junko Aimi, Sravanthi Cheeti, Jill O. Fredrickson, Stephanie Hilz, Marc A. Hafner, Katherine E. Hutchinson, Yanling Jin, Ubong Peters, Daniel Zingg, Stephanie Royer‐Joo, Noopur Shankar, Jennifer L. Schutzman, Komal L. Jhaveri, Anwesha Dey
DOI: 10.1158/1078-0432.31006702
Cited by: 0

Abstract

Drug combination effect of inavolisib and the FGFR2i as measured by a two-way 10 x 8 serial dilution matrix in a 5-day viability assay

Fields of Study & Subjects

Fibroblast Growth Factor Research Sympathectomy and Hyperhidrosis Treatments Eosinophilic Disorders and Syndromes

Publication details

Publication date
6 January 2026