Supplementary Figure S5 from Oxford Classic–Defined EMT Risk Stratification of High-Grade Serous Ovarian Cancer for Guiding Treatment Decisions

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Authors: Lena Rai, Antonella Ravaggi, Eliana Bignotti, Robert L. Hollis, Dale W. Garsed, Ahwan Pandey, Kyriaki Barbara Papalois, Faheemah Patel, Yasmin Kamel, Leticia Campo, Alistair Easton, Joel Nulsen
+17 more Breeshey Roskams-Hieter, Mara Artibani, Lili Wang, Nosheen Hussain, Luyao Wang, Nancy Zaarour, Aneesh Aggarwal, Amro Ahmed-Ebbiary, Aws Al-Deka, Michael Churchman, C. Simon Herrington, Laura Ardighieri, Federico Ferrari, Christopher Yau, Charlie Gourley, Franco Edoardo Odicino, Ahmed Ashour Ahmed
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Abstract

Supplementary Fig. S5. Representative images of an [A] OxC-EMT-high (patient BS137) and [B] OxC-EMT-low (patient BS141) tumour from the validation mIF experiments. [C] Violin plots demonstrating the difference in the abundance of M2 macrophages (CD206+ or CD206+CD163+) and CD8+TRM using immune cell counts normalised against total number of nuclei in each ROI.

Fields of Study & Subjects

Ovarian cancer diagnosis and treatment Immune cells in cancer PARP inhibition in cancer therapy

Publication details

Publication date
6 January 2026