Supplementary Figure S1 from Oxford Classic–Defined EMT Risk Stratification of High-Grade Serous Ovarian Cancer for Guiding Treatment Decisions

Supplementary Fig. S1. [A] Violin plot illustrating the distribution of OxC-EMT scores in 12 independent datasets. [B] Line graph of Hazard Ratios and associated p-values derived from fitting a loop structured cox regression model to the combined set. Y-axis on the left-hand side represents the scale for Hazard Ratio and the y-axis on the right-hand side represents the scale for the p-value. [C] Plot displaying median survival time (in days) for OxC-EMT-high (solid red line) and corresponding 95% CI (dashed red line) and median survival for OxC-EMT-low (solid blue line) and corresponding 95% CI (dashed blue line). [D] Kaplan-Meier survival plot demonstrating the probability of overall survival for OxC-EMT-high/BRCAmutated, OxC-EMT-high/BRCAwildtype, OxC-EMT-low/BRCAmutated and OxC-EMT-low/BRCAwildtype patients in the Scottish cohort. [E] Kaplan-Meier survival plot demonstrating the probability of overall survival for OxC-EMT-low risk patients in the Combined set with Oxford Classic subtypes, Cell Cycle, Differentiated, KRT17 and Mixed.