Supplementary Figure S2 from Accelerating Drug Development in Hormone-Naïve Prostate Cancer through Multimodal Therapy Strategies: The MetaCURE Phase 2 Randomized Clinical Trial

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Authors: Deaglan Joseph McHugh, Matthew C. Dallos, Min Yuen Teo, Sean M. McBride, Anuradha Gopalan, Andrea Arfè, Christopher Gaffney, Mehak Amjed, Patrick J. McCann, Hannah Benoliel, Karen A. Autio, A Goh
+22 more Kevin M DeRudder, Catherine J. Ryan, Russell Zelig Szmulewitz, Alicia Katherine Morgans, Glenn J. Bubley, Shilpa Gupta, Eric A. Klein, Paul L. Nguyen, Adam S. Kibel, Andrew A. Wagner, I.D. Kaplan, Scott E. Eggener, David Johnson Einstein, Andres Martin Acosta, Rahul D. Tendulkar, David James VanderWeele, William J. Catàlona, Sean Sachdev, Stanley L. Liauw, Jeff Eastham, Mary‐Ellen Taplin, Howard I. Scher
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Abstract

Supplementary Figure S2. Time to Testosterone Recovery by Cohort and Treatment Assignment. Cumulative probability curves depict time to testosterone recover measured from the end of systemic therapy among participants in Cohort A (red) and Cohort B (blue). Solid lines represent participants treated with ADT + Apa, while dashed lines represent those receiving ADT + Apa + AAP. The number of participants at risk at each time point is shown below the graph.

Fields of Study & Subjects

Prostate Cancer Treatment and Research Prostate Cancer Diagnosis and Treatment Bone health and treatments

Publication details

Publication date
4 February 2026