Figure 2 from TAPISTRY: A Phase II Study of Atezolizumab in Patients with Tumor Mutational Burden–High Tumors

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Authors: David William Thomas, Jeong Suk Kim, Fabrice Barlési, Uwe M. Martens, Maciej Jerzy Krzakowski, Rafał Dziadziuszko, Jae Ho Jeong, Gennaro Daniele, Timothy Richard Wilson, Felice Wu, Brian Simmons, Sid Patel
+3 more Maria Sbirnac, Monika Kaul, Shirish M. Gadgeel
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Abstract

Kaplan–Meier plots of (A) confirmed DOR and (B) PFS, as assessed by IRC in patients with TMB ≥13 mut/Mb per the enrollment assay. When using a TMB cutoff of ≥13 mut/Mb per the enrollment assay (n = 129), median DOR was NE, and median IRC-assessed PFS was 2.7 months (95% CI, 1.5–4.2). #, Remaining patients at the corresponding time point; +, a censoring event.

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Cancer Genomics and Diagnostics Lung Cancer Treatments and Mutations

Publication details

Publication date
16 March 2026
Language
EN