Table S2 from Identification of Small-Molecule Inhibitors that Block the GTP-Binding Pocket of K-Ras and Other Members of the Ras Superfamily of Small GTPases

Read full text
Authors: Luca Carta, Rebecca Hutcheson, Carolina L. Bigarella, Sufang Zhang, Simon A. Davis, Michael J. Rudolph, Charles H. Reynolds, Matthias Quick, Theresa M. Williams, Michael Schmertzler, Yaron R. Hadari
Cited by: 0

Abstract

IC50 values of sotorasib, adagrasib and RMC-6236 in the GTP binding assay (µM)

Fields of Study & Subjects

Protein Kinase Regulation and GTPase Signaling Biomedical Research and Pathophysiology Metabolism Diabetes and Cancer

Publication details

Publication date
2 January 2026