Figure S8 from Identification of Small-Molecule Inhibitors that Block the GTP-Binding Pocket of K-Ras and Other Members of the Ras Superfamily of Small GTPases

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Authors: Luca Carta, Rebecca Hutcheson, Carolina L. Bigarella, Sufang Zhang, Simon A. Davis, Michael J. Rudolph, Charles H. Reynolds, Matthias Quick, Theresa M. Williams, Michael Schmertzler, Yaron R. Hadari
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Abstract

Combination studies on cell proliferation of SHY-855 and SHY-867 in combination with adagrasib

Fields of Study & Subjects

Protein Kinase Regulation and GTPase Signaling Protein Tyrosine Phosphatases Cellular transport and secretion

Publication details

Publisher
American Association for Cancer Research (AACR)
Publication date
2 January 2026