Figure S7 from Identification of Small-Molecule Inhibitors that Block the GTP-Binding Pocket of K-Ras and Other Members of the Ras Superfamily of Small GTPases

2026 Open access

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Authors: Luca Carta, Rebecca Hutcheson, Carolina L. Bigarella, Sufang Zhang, Simon A. Davis, Michael J. Rudolph, Charles H. Reynolds, Matthias Quick, Theresa M. Williams, Michael Schmertzler, Yaron R. Hadari
DOI: 10.1158/1535-7163.30985742
Cited by: 0

Abstract

Compound SHY-867 inhibits K-Ras downstream signaling.

Fields of Study & Subjects

Protein Kinase Regulation and GTPase Signaling Protein Tyrosine Phosphatases Receptor Mechanisms and Signaling

Publication details

Publisher
American Association for Cancer Research (AACR)
Publication date
2 January 2026