Supplementary Fig. 1 from Targeting the ERα DBD–LBD Interface with Mitoxantrone Disrupts Receptor Function through Proteasomal Degradation

2026 Open access

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Authors: Han Wang, Yuxuan Luo, Sandeep Artham, Qianqian Wang, Yi Peng, Zixi Yun, Xinyue Li, Chen Wu, Zhenghao Liu, Kristen L. Weber-Bonk, Chun-Peng Pai, Yuan Cao
+7 more Jiangan Yue, Sunghee Park, Ruth A. Keri, Lisheng Geng, Donald Patrick McDonnell, Hung‐Ying Kao, Sichun Yang
DOI: 10.1158/1535-7163.30986033
Cited by: 0

Abstract

Supplementary Fig. 1: MTO, unlike fulvestrant, maintains E2-mediated ER-SRC3 interaction

Fields of Study & Subjects

Melanoma and MAPK Pathways Protein Degradation and Inhibitors Protein Kinase Regulation and GTPase Signaling

Publication details

Publisher
American Association for Cancer Research (AACR)
Publication date
2 January 2026