Supplementary Figure S4 from In Vivo Tumor Growth Control by General Control Nonderepressible 2–Targeting Agents Results from Kinase Activation

Feven Tameire; Paulina M. Wojnarowicz; Crissy Dudgeon; Kathryn T. Bieging-Rolett; Sho Fujisawa; Savi Ramurthy; Owen Reilly; Christopher G. Thomson; Bradley S. Sherborne; Simon J. Taylor; Fang He; Pengwei Pan; Baozhong Li; Earl W. May; Alan C. Rigby; Mark J. Mulvihill; Nandita Bose; David Surguladze; Eric S. Lightcap

doi:10.1158/1535-7163.30986228

Supplementary Figure S4 from In Vivo Tumor Growth Control by General Control Nonderepressible 2–Targeting Agents Results from Kinase Activation

2026 Open access

Read full text

Authors: Feven Tameire, Paulina M. Wojnarowicz, Crissy Dudgeon, Kathryn T. Bieging-Rolett, Sho Fujisawa, Savi Ramurthy, Owen Reilly, Christopher G. Thomson, Bradley S. Sherborne, Simon J. Taylor, Fang He, Pengwei Pan

+7 more

Baozhong Li, Earl W. May, Alan C. Rigby, Mark J. Mulvihill, Nandita Bose, David Surguladze, Eric S. Lightcap

DOI: 10.1158/1535-7163.30986228

Cited by: 0

Abstract

GCN2-targeting agents impact viability as inhibitors in the presence of amino acid deprivation caused by asparaginase, but not halofuginone

Fields of Study & Subjects

Retinoids in leukemia and cellular processes Protein Degradation and Inhibitors Synthesis of Organic Compounds

Publication details

Publication date: 2 January 2026