Supplementary Figure 4 from CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer

Ujas A. Patel; Mary Y. Shi; Jalal M. Kazan; Kevin C. J. Nixon; Xiaozhuo Ran; Sree Narayanan Nair; Olivia Huang; Lifang Song; Mansi K. Aparnathi; Michael Y. He; Mehran Bakhtiari; Rehna Krishnan; Razan K. Hessenow; Vivek Philip; Troy W. Ketela; Verena Jendrossek; Razqallah Hakem; Housheng Hansen He; Robert Kridel; Benjamin  Hoyin Lok

doi:10.1158/1535-7163.30986282

Supplementary Figure 4 from CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer

2026 Open access

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Authors: Ujas A. Patel, Mary Y. Shi, Jalal M. Kazan, Kevin C. J. Nixon, Xiaozhuo Ran, Sree Narayanan Nair, Olivia Huang, Lifang Song, Mansi K. Aparnathi, Michael Y. He, Mehran Bakhtiari, Rehna Krishnan

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Razan K. Hessenow, Vivek Philip, Troy W. Ketela, Verena Jendrossek, Razqallah Hakem, Housheng Hansen He, Robert Kridel, Benjamin Hoyin Lok

DOI: 10.1158/1535-7163.30986282

Cited by: 0

Abstract

The combination of HDAC3 loss and IR improves tumor control in SCLC xenografts.

Fields of Study & Subjects

Lung Cancer Research Studies Histone Deacetylase Inhibitors Research Lung Cancer Treatments and Mutations

Publication details

Publication date: 2 January 2026