Supplementary Figure 3 from CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer

2026 Open access

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Authors: Ujas A. Patel, Mary Y. Shi, Jalal M. Kazan, Kevin C. J. Nixon, Xiaozhuo Ran, Sree Narayanan Nair, Olivia Huang, Lifang Song, Mansi K. Aparnathi, Michael Y. He, Mehran Bakhtiari, Rehna Krishnan
+8 more Razan K. Hessenow, Vivek Philip, Troy W. Ketela, Verena Jendrossek, Razqallah Hakem, Housheng Hansen He, Robert Kridel, Benjamin Hoyin Lok
DOI: 10.1158/1535-7163.30986285
Cited by: 0

Abstract

Cells with HDAC3 loss have increased generation and persistence of DNA DSBs.

Fields of Study & Subjects

Lung Cancer Research Studies Histone Deacetylase Inhibitors Research Lung Cancer Treatments and Mutations

Publication details

Publisher
American Association for Cancer Research (AACR)
Publication date
2 January 2026