Supplementary Figure 5 from Pharmacogenomic Synthetic Lethal Screens Reveal Hidden Vulnerabilities and New Therapeutic Approaches for Treatment of NF1-Associated Tumors

Kyle Brandon Williams; Alex T. Larsson; Bryant J. Keller; Katherine E. Chaney; Rory L. Williams; Minu M. Bhunia; Garrett M. Draper; Tyler A. Jubenville; Wendy A. Hudson; Gunda I. Georg; Christopher L. Moertel; Nancy Ratner; David A. Largaespada

doi:10.1158/1535-7163.31248665

Supplementary Figure 5 from Pharmacogenomic Synthetic Lethal Screens Reveal Hidden Vulnerabilities and New Therapeutic Approaches for Treatment of NF1-Associated Tumors

2026 Open access

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Authors: Kyle Brandon Williams, Alex T. Larsson, Bryant J. Keller, Katherine E. Chaney, Rory L. Williams, Minu M. Bhunia, Garrett M. Draper, Tyler A. Jubenville, Wendy A. Hudson, Gunda I. Georg, Christopher L. Moertel, Nancy Ratner

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David A. Largaespada

DOI: 10.1158/1535-7163.31248665

Cited by: 0

Abstract

Supplementary Figure 5 shows the drug dose response curves of NF1 -/- vs NF1 ± cells treated with the drugs of interest in this study.

Fields of Study & Subjects

Neurofibromatosis and Schwannoma Cases Protein Tyrosine Phosphatases Chromatin Remodeling and Cancer

Publication details

Publication date: 4 February 2026