DI-Compounds Synthesis from Dual Inhibitors of KRASG12D and HSP90 Are Effective against KRASG12D Inhibitor Resistance

Inés Pulido; Laura C. Gunder; Chenghao Ying; Yaya Wang; Yan Dai; Zimo Yang; Alireza Rahnama; Jinhua Li; Yuetong Sun; Chuhe Liu; Haoxin Zhou; Guoqiang Wang; Kevin P. Foley; Khaled Abdelhady; Malek G. Massad; Thomas L. Prince; Ian Papautsky; Weiwen Ying; Takeshi Shimamura

doi:10.1158/1535-7163.31248779

DI-Compounds Synthesis from Dual Inhibitors of KRASG12D and HSP90 Are Effective against KRASG12D Inhibitor Resistance

2026 Open access

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Authors: Inés Pulido, Laura C. Gunder, Chenghao Ying, Yaya Wang, Yan Dai, Zimo Yang, Alireza Rahnama, Jinhua Li, Yuetong Sun, Chuhe Liu, Haoxin Zhou, Guoqiang Wang

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Kevin P. Foley, Khaled Abdelhady, Malek G. Massad, Thomas L. Prince, Ian Papautsky, Weiwen Ying, Takeshi Shimamura

DOI: 10.1158/1535-7163.31248779

Cited by: 0

Fields of Study & Subjects

Protein Kinase Regulation and GTPase Signaling Synthesis and biological activity Melanoma and MAPK Pathways

Publication details

Publication date: 4 February 2026